| Hugh Grant | ... Samuel Faulkner |
| Julianne Moore | ... Rebecca Taylor |
| Tom Arnold | ... Marty Dwyer |
| Joan Cusack | ... Gail Dwyer |
| Jeff Goldblum | ... Sean Fletcher |
| Robin Williams | ... Dr. Kosevich |
| Mia Cottet | ... Lili |
| Joey Simmrin | ... Truman |
| Ashley Johnson | ... Shannon Dwyer |
| Alexa Vega | ... Molly Dwyer |
| Aislin Roche | ... Patsy Dwyer |
| Priscilla Alden | ... Older Woman |
| Edward Ivory | ... Older Man |
| James M. Brady | ... Bicyclist |
| Charles A. Martinet | ... Arnie |
| Brendan Columbus | ... Little Boy on Beach |
| Eleanor Columbus | ... 'Little Girl in Ballet Class #1 |
| Anna Barnathan | ... Little Girl #2 in Ballet Class |
| Zelda Williams | ... Little Girl #3 in Ballet Class |
| Peter Bankins | ... Tow Truck Driver |
| Betsy Monroe | ... Bobbie |
| Ngaio S. Bealum | ... Sean's Friend #1 |
| Cynthia Urquhart | ... Sean's Friend #2 |
| Tim Moffett | ... Sean's Friend #3 |
| Mia Liban | ... Sean's Friend #4 |
| Kumar Singh | ... Sean's Friend #5 |
| Amanda Girard | ... Praying Mantis |
| Val Diamond | ... Dr. Kosevich's Receptionist |
| Jerry Masan | ... Clown Outside Toy Store |
| Irene Columbus | ... Woman in Toy Store |
| Violet Columbus | ... Baby in Toy Store |
| Brittany Radcliffe | ... Child #1 at Toy Store |
| Porscha Radcliffe | ... Child #2 at Toy Store |
| Cody Lee Dorkin | ... Child #3 at Toy Store |
| Emily Gosnell | ... Child #4 at Toy Store |
| Bradley Gosnell | ... Child #5 at Toy Store |
| Kristin Davis | ... Tennis Attendant |
| Angela Hopkins | ... Ultrasound Receptionist |
| Emily Yancy | ... Dr. Thatcher |
| Hayley Rose Hansen | ... Baby in Ultrasound |
| Shawn Cady | ... Roller Blade Girl |
| George F. Mauricio | ... Moving Man |
| Paul Simon | ... Car Salesman |
| Frank P. Verducci | ... Car Lot Customer #1 |
| Barbara Olson | ... Car Lot Customer #2 |
| Morgan Miller | ... Kid Being Choked in Park |
| Carol DePasquale | ... Maternity Floor Receptionist |
| Bruce Devan | ... Doctor in Hallway |
| Cheryl Lee Thorup | ... Christine |
| Clarke Devereux | ... Emergency Attendant #1 |
| Tommy Banks | ... Emergency Attendant #2 |
| Susan Ilene Johnson | ... Delivery Room Head Nurse |
| Maureen McVerry | ... Pregnant Woman #1 |
| Velina Brown | ... Pregnant Woman #2 |
| Joy M. Cook | ... Pregnant Woman #3 |
| Sue Murphy | ... Pregnant Woman #4 |
| Lee Ann Manley | ... Pregnant Woman #5 |
| Diane Amos | ... Rebecca's Nurse |
| Betsy Aidem | ... Gail's Nurse |
| Terence McGovern | ... Anesthesiologist |
| Geoff Bolt | ... Male Delivery Room Nurse |
| Gwen Holloway | ... Female Delivery Room Nurse |
