| Javier Bardem | ... Florentino Ariza |
| Giovanna Mezzogiorno | ... Fermina Urbino |
| Benjamin Bratt | ... Dr. Juvenal Urbino |
| Catalina Sandino Moreno | ... Hildebranda |
| Hector Elizondo | ... Don Leo |
| Liev Schreiber | ... Lotario Thugut |
| Ana Claudia Talancón | ... Olimpia Zuleta |
| Fernanda Montenegro | ... Tránsito Ariza |
| Unax Ugalde | ... Florentino (Teen) |
|
| with |
| Laura Harring | ... Sara Noriega |
| John Leguizamo | ... Lorenzo Daza |
|
| Alicia Borrachero | ... Escolástica |
| Angie Cepeda | ... Widow Nazaret |
| Marcela Mar | ... America Vicuña |
|
| Gina Bernard Forbes | ... Digna Pardo |
| Juan Angel | ... Marco Aurelio (40s) |
| Liliana Alvarez Gonzalez | ... Marco Aurelio's Wife |
| Catalina Botero | ... Ofelia Urbino (40s) |
| Miguel Angel Pazos Galindo | ... Ofelia's Husband |
| Maria Cecilia Herrera | ... Urbino's Sweet Wife |
| Luis Fernando Hoyos | ... Urbino Urbino |
| Carlos Duplat | ... Mourner |
| Francisco Raul Linero | ... Mourner |
| Julieth Paola Hoyos Zuñiga | ... Barefoot Maid |
| Padre Gerardo Norberto Arango Echeverri | ... Priest |
| Dora Cadavid | ... Mother Superior |
| María Eugenia Arboleda | ... Gala Placidia |
| Marta Helena Sawades Rodriguez | ... Lotario Whore |
| Lisseth Janeth Figueroa Manzur | ... Lotario Whore |
| Denis Mercado Moreno | ... Lotario Whore |
| Beatriz Colombia Ospino | ... Aging Whore |
| Jhon Alexander Toro | ... Ricardo Lighthouse |
| Julián Diaz | ... Sweet Seller |
| Jose Luis Garcia Campos | ... Porter |
| Manuel Sarmiento | ... Belgian Photographer |
| Rodolfo Enrique Mercado Parra | ... Benny Centeno |
| Fernando Cajales | ... Don Leo's Clerk |
| Luis Adolfo Tamara Cardona | ... First Mate's Voice |
| Rafael Vergara | ... Captain's Voice |
| Andres Casas | ... Cholera Boat Man |
| Rubria Negrão | ... Rosalba |
| Antonio Jose de Lavalle Ospino | ... Child 7 Years Old |
| Oscar Ezequiel Padilla Garcia | ... Panic Child |
| Ivan Diaz Pombo | ... The Sailor |
| Noëlle Schonwald | ... Attractive Woman |
| Paola Turbay | ... Attractive Woman |
| Maria Alejandra Fuentes Atencia | ... Trolley Skinny Girl |
| Eliris Sierra Gomez | ... Thin Black Woman |
| Luis Fernando Gil Caldera | ... Paper Seller |
| Andrés Castañeda | ... Handsome Youth |
| Nicolas Bolaño Villamil | ... Baptism Priest |
| Samuel Aguilar | ... Marco Aurelio (Newborn) |
| Maria Teresa Mateos Romero | ... Young Girl |
| Alejandra Borrero | ... Doña Blanca |
| Patricia Castañeda | ... Grand Lady |
| Laura Garcia Marulanda | ... Grand Lady |
| Rita Bendek | ... Grand Lady |
| Rosario Jaramillo | ... Grand Lady |
| Maria Carolina Cuervo | ... Grand Lady Daughter |
| Alfonso Wong Mah | ... Wing Wu Peng |
| Margalida Castro Rueda | ... Governess |
| Ena Ortega de Insignares | ... Woman with Transito |
| Marina Chirolla | ... Old Nurse |
| Miguel Canal | ... Boy with Cage |
| Horacio Tavera | ... Diego |
| Salvatore Basile | ... City Mayor |
| Adriana Cantor | ... Andrea Varón |
| Indhira Serrano | ... Dr. Barbara Lynch |
| Nohemi Millan | ... La Boheme Singer Female |
| Isaac Jos Ricardo Aldana | ... La Boheme Singer Male |
| Luis Alberto Moreno Ruiz | ... Hudson's Driver |
| Juan Antonio Restom Bitar | ... Florentino's Clerk |
| Andres Parra | ... Capt. Samaritano |
