| Jack Lemmon | ... Russell P. Kramer |
| James Garner | ... Matt Douglas |
| Dan Aykroyd | ... William Haney |
| John Heard | ... Ted Matthews |
| Wilford Brimley | ... Joe Hollis |
| Lauren Bacall | ... Margaret Kramer |
| Sela Ward | ... Kaye Griffin |
| Everett McGill | ... Col. Paul Tanner |
| Bradley Whitford | ... Carl Witnaur |
| James Rebhorn | ... Charlie Reynolds |
| Esther Rolle | ... Rita |
| Conchata Ferrell | ... Woman Truck Driver |
| Jack Kehler | ... Wayne |
| Connie Ray | ... Genny |
| Tom Everett | ... Wilkerson |
| Mark Lowenthal | ... Caldwell |
| Jeff Yagher | ... Dorothy / Lt. Ralph Fleming |
|
| In order of appearance |
| Edwin Newman | ... Himself |
| Lynn Clark | ... Chrissy Kramer |
| Leigh Rose | ... Katherine Douglas |
| Mihoko Tokoro | ... Japanese Singer |
| Ken Enomoto | ... Hiroshi Ashino |
| Gunnar Peterson | ... Bruce |
| Scott Burkholder | ... Greg |
| Wayne Duvall | ... Chet |
| Jack Garner | ... President Haney's Caddy |
| Gene Bolande | ... Injured Golf Spectator |
| Francesca Rollins | ... Reporter #1 |
| Paul Feig | ... Reporter #2 |
| Cathy Ladman | ... Reynolds' Secretary |
| Tom Wright | ... Jim |
| Dana Gould | ... Sandwich Guy at Book Convention |
| Scott Hoxby | ... Man with Subpoena |
| Jonathan Osser | ... Kramer's Grandson |
| Mitch Braswell | ... Marine One Pilot |
| Art Booth | ... Marine One Co-Pilot |
| Steve Carlisle | ... Man in Train Station Bathroom |
| Todd McDurmont | ... Elvis |
| Madison Wellington | ... Tina |
| David "Skippy" Malloy | ... Will |
| Jennifer L. Jones | ... Fran |
| Rob Roy Fitzgerald | ... Dean |
| Jennifer Austin | ... Marilyn Monroe |
| Bobby Bass | ... NSA Hit Man #1 |
| Steve Chambers | ... NSA Hit Man #2 |
| Jimmy Nickerson | ... NSA Hit Man #3 |
| Cara Gooden | ... Truck Stop Girl |
| Matt Zboyovski | ... Truck Stop Boy |
| Michael Peņa | ... Ernesto |
| Alex Joganic | ... Kevin |
| Ocie Pouncie | ... Man in Diner |
| Neva Howell | ... Charlene -- Budget Agent |
| Sheri Mann Stewart | ... Sandy -- Budget Agent |
| Pete Penuel | ... Man in Parade |
| John O'Leary | ... Caretaker Ben |
| Leighanne Wallace | ... Witnaur's Girlfriend |
| Rick Hall | ... White House Guard |
| Eric Siegel | ... President Haney's Aide |
| Ann Cusack | ... White House Tour Guide |
| Jean Speegle Howard | ... Asthmatic Woman on Tour |
| Dorothy Lucey | ... News Anchor |
| Jeff Mandon | ... Secret Service Agent |
| James Bissell | ... Secret Service Agent |
| Shawn D. Woodyard | ... Secret Service Agent |
| Stephen Wedan | ... Mounted Police #1 |
| Tom Sean Foley | ... Mounted Police #2 |
| Michael Russo | ... White House Sharpshooter |
| Chris Kriesa | ... Agent Kopeck |
| William Kerr | ... V.P. Matthews' Make-Up Man |
| Peter Segal | ... TV Technician |
