Father: Rezin Pleasant Bowie (d. 1821)
Mother: Alvina Ap-Catesby Jones ("Elve", d. 1838)
Brother: John Jones Bowie (b. 1785, d. 1859)
Sister: Sarah Bowie Davis (b. 1787)
Sister: Mary Bowie Bird (b. 1789)
Sister: Martha Bowie Sterrett (b. 1791)
Brother: Rezin Pleasant Bowie, Jr. (b. 8-Sep-1793, d. 17-Jan-1841)
Brother: David Bowie (d. drowning)
Brother: Stephen Bowie (b. 1797, d. 1833)
Girlfriend: Cecelia Wells (engaged, d. 7-Sep-1829)
Wife: Ursula Maria de Veramendi (m. 25-Apr-1831, d. Sep-1833 cholera)