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Peter Agre

Peter AgreAKA Peter Courtland Agre

Born: 30-Jan-1949
Birthplace: Northfield, MN

Gender: Male
Religion: Lutheran
Race or Ethnicity: White
Sexual orientation: Straight
Occupation: Biologist, Chemist
Party Affiliation: Democratic

Nationality: United States
Executive summary: Water channels of cell membranes

American hematologist Peter Agre (pronounced AHG-ray) won the Nobel Prize for Chemistry in 2003, for his 1991 discovery of aquaporins, proteins embedded in cell membranes that regulate and facilitate the flow of water molecules across and into cells, a process essential for life as we know it. Aquaporins form a channel in the membrane, allowing billions of water molecules to diffuse across the membrane every second, and serving as a river-like barrier to prevent other ions or molecules from crossing the channel. Agre has said that aquaporins are "the plumbing system for cells", and the potential applications of his discovery include the development of drugs to address brain edema following a stroke, fluid retention problems in heart disease, or virtually any other disease characterized by excess or inadequate fluids.

Father: Courtland Agre (chemist)
Mother: Ellen Swedberg
Sister: Annetta (b. 1946)
Brother: James (physician, b. 1950)
Brother: Paul (mentally retarded)
Sister: Ruth
Brother: Mark (physician)
Wife: Mary Macgill (m. 29-Mar-1975)
Daughter: Sara (b. 1978)
Daughter: Claire
Daughter: Lydia (b. 1983, d. 21-Dec-1983)
Son: Clarke (b. 1985)

    High School: Theodore Roosevelt High School, Minneapolis, MN (night school, 1967)
    University: University of Minnesota (attended, 1967)
    University: BA Chemistry, Augsburg College (1970)
    Medical School: MD, Johns Hopkins University (1974)
    Scholar: Pharmacology, Johns Hopkins University (1974-75)
    Scholar: Internship, Case Western Reserve University (1975-78)
    Teacher: Hematology and Oncology, University of North Carolina at Chapel Hill (1978-81)
    Teacher: Biological Chemistry, Johns Hopkins University (1981-93)
    Professor: Biological Chemistry, Johns Hopkins University (1993-2005)
    Professor: Cell Biology, Duke University (2005-)
    Administrator: Vice Chancellor for Science and Technology, Duke University (2005-)

    Eagle Scout 1964
    Nobel Prize for Chemistry 2003 (with Roderick MacKinnon)
    Distinguished Eagle Scout Award
    Howard Hughes Medical Institute Scientific Review Board (2003-)
    Carnegie Institution for Science Embryology Lab (1988-89)
    Blood Editorial Board (1993-97)
    Journal of Biological Chemistry Editorial Board (1999-2002)
    Journal of Clinical Investigation Editorial Board (1993-)
    Academy of Achievement 2004
    American Academy of Arts and Sciences
    American Association for the Advancement of Science President (2009-10)
    American Philosophical Society
    American Physiological Society
    American Society for Biochemistry and Molecular Biology
    American Society for Cell Biology
    American Society for Clinical Investigation
    American Society of Hematology
    American Society of Nephrology
    Boy Scouts of America (childhood)
    Federation of American Scientists Board of Sponsors
    National Academy of Sciences 2000
    Science Debate 2008
    Scientists and Engineers for America
    Norwegian Ancestry Paternal and Maternal
    Swedish Ancestry Maternal
    Risk Factors: Hepatitis

Author of books:
Aquaporins (2001, chemistry; with Stefan Hohmann and Søren Nielsen)


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