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Edwin G. Krebs

Edwin G. KrebsAKA Edwin Gerhard Krebs

Born: 6-Jun-1918
Birthplace: Lansing, IA
Died: 21-Dec-2009
Location of death: Seattle, WA
Cause of death: Heart Failure

Gender: Male
Race or Ethnicity: White
Sexual orientation: Straight
Occupation: Scientist, Doctor

Nationality: United States
Executive summary: Protein phosphorylation

Military service: US Navy (1944-46)

American biochemist Edwin G. Krebs discovered reversible protein phosphorylation, the biological regulatory mechanism that controls most human cells. He spent two years studying rabbit muscle with Nobel laureates Carl and Gerty Cori, before spending many years in close collaboration with Edmond H. Fischer at the University of Washington. Often referred to by colleagues as "the two Eds", they worked together so closely that, Krebs said, "if one had to leave to give a lecture the other could carry on the experiment of the day".

Krebs and Fischer were jointly awarded the Nobel Prize for Medicine or Physiology in 1992. Krebs picked up the tab to bring everyone in his extended family to his Nobel ceremonies in Stockholm, then gave the remainder of his winnings to assorted charities. He was not related to Nobel laureate Hans Krebs.

Father: William Carl Krebs (Presbyterian minister, d. 1933)
Mother: Louise Helen Stegeman Krebs
Wife: Virginia Deedy French Krebs (nurse, m. 10-Mar-1945, until his death, two daughters, one son)
Daughter: Sally Herman
Son: Robert Krebs
Daughter: Martha Abrego

    High School: Urbana High School, Urbana, IL (1936)
    University: BS, University of Illinois at Urbana-Champaign (1940)
    Medical School: MD, Washington University in St. Louis (1943)
    Scholar: Biochemistry, Washington University in St. Louis (1946-48)
    Teacher: Biochemistry, University of Washington (1948-57)
    Professor: Biochemistry, University of Washington (1957-68)
    Professor: Biological Chemistry, University of California at Davis (1968-77)
    Professor: Pharmacology, University of Washington (1977-)

    Federation of American Scientists Board of Sponsors
    Howard Hughes Medical Institute Investigator (1977-83)
    Lasker Award 1989
    Nobel Prize for Medicine 1992 (with Edmond H. Fischer)

Author of books:
The Enzymes (1970, with Paul D. Boyer and D S Sigman)
Protein Phosphorylation (1981, with Ora M Rosen)
Control by Phosphorylation (1986, with Paul D. Boyer)


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