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Earl W. Sutherland, Jr.

Earl W. Sutherland, Jr.AKA Earl Wilbur Sutherland, Jr.

Born: 19-Nov-1915
Birthplace: Burlingame, KS
Died: 9-Mar-1974
Location of death: Miami, FL
Cause of death: Complications of Surgery
Remains: Buried, Burlingame City Cemetery, Burlingame, KS

Gender: Male
Race or Ethnicity: White
Sexual orientation: Straight
Occupation: Scientist, Doctor

Nationality: United States
Executive summary: Hormones mechanisms (cyclic AMP)

Military service: US Army (battalion surgeon, WWII)

American biochemist Earl Sutherland Jr was inspired to pursue medical research when he read a book about Louis Pasteur. In World War II he served as a battalion surgeon under George S. Patton, and after the war he spent his career studying how hormones regulate body functions. He studied epinephrine with Nobel laureates Carl and Gerty Cori, and showed how adrenaline regulates the way sugar is broken down, providing a surge of energy when the body is under stress. In his most famous work, he discovered cyclic adenosine 3'5'-monophosphate (cyclic AMP), a "second messenger" which regulates numerous intracellular reactions. Sutherland received the Nobel Prize in Medicine or Physiology in 1971, for "his long study of hormones, the chemical substances that regulate virtually every body function."

Father: Earl Wilbur Sutherland (owned a dry-goods store)
Mother: Edith M. Hartshorn Sutherland
Wife: Mildred Rice Sutherland (m. 1937, div. 1962)
Wife: Claudia Sebeste Smith Sutherland (assistant dean at Vanderbilt University, m. 1963)

    High School: Burlingame Junior/Senior High School, Burlingame, KS (1932)
    University: BS Chemistry, Washburn University (1937)
    Medical School: MD, Washington University in St. Louis (1942)
    Teacher: Pharmacology, Washington University in St. Louis (1940-46)
    Teacher: Biochemistry, Washington University in St. Louis (1946-53)
    Professor: Pharmacology, Case Western Reserve University (1953-63)
    Professor: Physiology, Vanderbilt University (1963-73)
    Professor: Biochemistry, University of Miami Florida (1973-74)

    Dickson Prize 1970
    Lasker Award 1970
    Nobel Prize for Medicine 1971
    National Medal of Science 1973
    Alpha Omega Alpha Honor Society
    American Association for the Advancement of Science
    American Chemical Society
    American Heart Association Career Investigator grant (1967)
    American Society for Biochemistry and Molecular Biology
    National Academy of Sciences
    Sigma Xi Scientific Research Society

Author of books:
Cyclic AMP (1971, with Reginald W. Butcher and G. Alan Robison)


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